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1

Regulation of P-glycoprotein expression in brain capillaries in Huntington’s disease and its impact on brain availability of antipsychotic agents risperidone and paliperidone

Kao, Yu-Han, Chern, Yijuang, Yang, Hui-Ting, Chen, Hui-Mei, Lin, Chun-Jung

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

2

The adenosine A 2A receptor agonist T1–11 ameliorates neurovisceral symptoms and extends the lifespan of a mouse model of Niemann-Pick type C disease

Ferrante, Antonella, Pezzola, Antonella, Matteucci, Andrea, Di Biase, Antonella, Attorri, Lucilla, Armida, Monica, Martire, Alberto, Chern, Yijuang, Popoli, Patrizia

Journal:

Neurobiology of Disease

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

3

Design and Synthesis of Novel Dual-Action Compounds Targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection

Jhih-Bin Chen, Eric Minwei Liu, Ting-Rong Chern, Chieh-Wen Yang, Chia-I Lin, Prof. Nai-Kuei Huang, Yun-Lian Lin, Prof. Yijuang Chern, Prof. Jung-Hsin Lin, Prof. Jim-Min Fang

Journal:

Year:

2011

Language:

english

File:

PDF, 677 KB

english, 2011

4

The A2A adenosine receptor rescues neuritogenesis impaired by p53 blockage via KIF2A, a kinesin family member

Chung-Nan Sun, Hsiu-Chun Chuang, Jiz-Yuh Wang, Si-Ying Chen, Ya-Yun Cheng, Chien-Fei Lee, Yijuang Chern

Journal:

Developmental Neurobiology

Year:

2010

Language:

english

File:

PDF, 2.63 MB

english, 2010

5

Activation of Phosphodiesterase IV During Desensitization of the A2A Adenosine Receptor-Mediated Cyclic AMP Response in Rat Pheochromocytoma (PC12) Cells

Yu-Hsin Chang, Marco Conti, Yi-Chao Lee, Hsing-Lin Lai, Yung-Hao Ching, Yijuang Chern

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

6

Modulation of Dopamine Transporter Activity by Nicotinic Acetylcholine Receptors and Membrane Depolarization in Rat Pheochromocytoma PC12 Cells

Chuen-Lin Huang, Hsiao-Chun Chen, Nai-Kuei Huang, De-Ming Yang, Lung-Sen Kao, Jin-Chung Chen, Hsing-Lin Lai, Yijuang Chern

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

7

Hydrogen peroxide induces loss of dopamine transporter activity: a calcium-dependent oxidative mechanism

Chuen-Lin Huang, Nai-Kuei Huang, Song-Kun Shyue, Yijuang Chern

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

8

Targeting Glial Cells to Elucidate the Pathogenesis of Huntington’s Disease

Han-Yun Hsiao, Yijuang Chern

Journal:

Molecular Neurobiology

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

9

Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanisms

Yen-Ching Wu, Rebecca Williamson, Zhi Li, Annalisa Vicario, Jerry Xu, Masataka Kasai, Yijuang Chern, Enrico Tongiorgi, Jay M. Baraban

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 671 KB

english, 2011

10

Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)

Chen-Li Chien, Yu-Shuo Wu, Hsing-Lin Lai, Yen-Hui Chen, Si-Tse Jiang, Chia-Ming Shih, Sui-Shan Lin, Chen Chang, Yijuang Chern

Journal:

Year:

2010

Language:

english

File:

PDF, 2.06 MB

english, 2010

11

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease

Ming-Chang Chiang, Yijuang Chern, Rong-Nan Huang

Journal:

Neurobiology of Disease

Year:

2012

Language:

english

File:

PDF, 754 KB

english, 2012

12

Regulation of adenylyl cyclase in the central nervous system

Journal:

Cellular Signalling

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

13

Structural role of amino acids 99–110 in recombinant human erythropoietin

Yijuang CHERN, Taeowan CHUNG, Arthur J. SYTKOWSKI

Journal:

Year:

1991

Language:

english

File:

PDF, 587 KB

english, 1991

14

Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats

Ingo Uphues, Yijuang Chern, Jürgen Eckel

Journal:

Year:

1995

Language:

english

File:

PDF, 481 KB

english, 1995

15

Circadian rhythm in the Ca2+-inhibitable adenylyl cyclase activity of the rat striatum

Yijuang Chern, Eminy H.Y. Lee, Hsing-Lin Lai, Hai-Long Wang, Yi-Chao Lee, Yung-Hao Ching

Journal:

Year:

1996

Language:

english

File:

PDF, 366 KB

english, 1996

16

Supraspinal contribution to splanchnic sympathetic activity in neonatal mouse and rat brainstem–spinal cord in vitro

Chun-Kuei Su, Yu-Pei Fan, Chien-Chang Chen, Yijuang Chern

Journal:

Autonomic Neuroscience

Year:

2010

Language:

english

File:

PDF, 534 KB

english, 2010

17

The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease

Ming-Chang Chiang, Yijuang Chern, Chiun-Gung Juo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

18

Spt4 Is Selectively Required for Transcription of Extended Trinucleotide Repeats

Chia-Rung Liu, Chuang-Rung Chang, Yijuang Chern, Tzu-Han Wang, Wen-Chieh Hsieh, Wen-Chuan Shen, Chi-Yuan Chang, I-Chieh Chu, Ning Deng, Stanley N. Cohen, Tzu-Hao Cheng

Journal:

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

19

Aspects of the general biology of adenosine A2A signaling

Bertil B. Fredholm, Yijuang Chern, Rafael Franco, Michail Sitkovsky

Journal:

Progress in Neurobiology

Year:

2007

Language:

english

File:

PDF, 876 KB

english, 2007

20

Expression of type VI adenylyl cyclase in the central nervous system: implication for a potential regulator of multiple signals in different neurotransmitter systems

Fu-Chin Liu, Gour-Cheng Wu, Sung-Tsang Hsieh, Hsing-Lin Lai, Hsiao-Fang Wang, Tsu-Wei Wang, Yijuang Chern

Journal:

Year:

1998

Language:

english

File:

PDF, 695 KB

english, 1998

21

Identification of nuclear factor 1 (NF1) as a transcriptional modulator of rat A2A adenosine receptor

Yi Chao Lee, Hsing Lin Lai, Chung Nan Sun, Chen Li Chien, Yijuang Chern

Journal:

Molecular Brain Research

Year:

2003

Language:

english

File:

PDF, 994 KB

english, 2003

22

Neuroprotective Principles from Gastrodia elata

Huang, Nai-Kuei, Chern, Yijuang, Fang, Jim-Min, Lin, Chia-I, Chen, Wan-Ping, Lin, Yun-Lian

Journal:

Journal of Natural Products

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

23

Enhancement of brain-type creatine kinase activity ameliorates neuronal deficits in Huntington's disease

Lin, Yow-Sien, Cheng, Tzu-Hao, Chang, Chin-Pang, Chen, Hui-Mei, Chern, Yijuang

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 1.42 MB

english, 2013

24

Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB

Tz-Chuen Ju, Yow-Sien Lin, Yijuang Chern

Journal:

Cellular and Molecular Life Sciences

Year:

2012

Language:

english

File:

PDF, 534 KB

english, 2012

25

Neurovascular abnormalities in brain disorders: highlights with angiogenesis and magnetic resonance imaging studies

Chen, Chiao-Chi V, Chen, Yu-Chen, Hsiao, Han-Yun, Chang, Chen, Chern, Yijuang

Journal:

Journal of Biomedical Science

Year:

2013

Language:

english

File:

PDF, 793 KB

english, 2013

26

A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor

Wu, Yi-Chih, Lai, Hsing-Lin, Chang, Wei-Cheng, Lin, Jiun-Tsai, Liu, Yu-Ju, Chern, Yijuang

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

27

Contents of volume 16

Wu, Yi-Chih, Lai, Hsing-Lin, Chang, Wei-Cheng, Lin, Jiun-Tsai, Liu, Yu-Ju, Chern, Yijuang

Journal:

Journal of Biotechnology

Year:

1990

Language:

english

File:

PDF, 78 KB

english, 1990

28

Molecular Cloning of a Novel Adenosine Receptor Gene from Rat Brain

Chern, Yijuang, King, Klim, Lai, Hsing-Lin, Lai, Hsing-Tsu

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 323 KB

english, 1992

29

Lack of type VI adenylyl cyclase (AC6) leads to abnormal sympathetic tone in neonatal mice

Chien, Chen-Li, Lin, Meng-Syuan, Lai, Hsing-Lin, Wu, Yu-Shuo, Chang, Ching-Pang, Chen, Huei-Mei, Chang, Chen, Su, Chun-Kuei, Chern, Yijuang

Journal:

Experimental Neurology

Year:

2013

Language:

english

File:

PDF, 754 KB

english, 2013

30

Neurovascular abnormalities in humans and mice with Huntington's disease

Lin, Chien-Yuan, Hsu, Yi-Hua, Lin, Ming-Huang, Yang, Tsai-Hui, Chen, Hui-Mei, Chen, Yu-Chen, Hsiao, Han-Yun, Chen, Chiao-Chi, Chern, Yijuang, Chang, Chen

Journal:

Experimental Neurology

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

31

AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

Ju, Tz-Chuen, Chen, Hui-Mei, Chen, Yu-Chen, Chang, Ching-Pang, Chang, Chen, Chern, Yijuang

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 3.62 MB

english, 2014

32

Characterization of the Rat A2a Adenosine Receptor Gene

CHU, YING-YUEH, TU, KE-HSIN, LEE, YI CHAO, KUO, ZHENG-JIE, LAI, HSIN-LIN, CHERN, YIJUANG

Journal:

DNA and Cell Biology

Year:

1996

Language:

english

File:

PDF, 5.27 MB

english, 1996

33

Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis

Liu, Yu-Ju, Lee, Li-Ming, Lai, Hsing-Lin, Chern, Yijuang

Journal:

Year:

2015

Language:

english

File:

PDF, 2.36 MB

english, 2015

34

Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism

Shen, Wen-Chuan, Li, Huei-Ying, Chen, Guang-Chao, Chern, Yijuang, Tu, Pang-hsien

Journal:

Year:

2015

Language:

english

File:

PDF, 4.65 MB

english, 2015

35

Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown

Cheng, Hui-Min, Chern, Yijuang, Chen, I-Hui, Liu, Chia-Rung, Li, Sih-Huei, Chun, Seung J., Rigo, Frank, Bennett, C. Frank, Deng, Ning, Feng, Yanan, Lin, Chyuan-Sheng, Yan, Yu-Ting, Cohen, Stanley N.,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

36

AMPK-mediated regulation of neuronal metabolism and function in brain diseases

Liu, Yu-Ju, Chern, Yijuang

Journal:

Journal of Neurogenetics

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

37

Novel Regulation of Adenylyl Cyclases by Direct Protein-Protein Interactions: Insights from Snapin and Ric8a

Wang, Shyi-Chyi, Lin, Jiun-Tsai, Chern, Yijuang

Journal:

Year:

2009

Language:

english

File:

PDF, 591 KB

english, 2009

38

A Critical Evaluation of Adenosine A2A Receptors as Potentially “Druggable” Targets in Huntingtons Disease

Popoli, Patrizia, Blum, David, Domenici, Maria, Burnouf, Sylvie, Chern, Yijuang

Journal:

Current Pharmaceutical Design

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

39

Aberrant astrocytes impair vascular reactivity in Huntington disease

Hsiao, Han-Yun, Chen, Yu-Chen, Huang, Chien-Hsiang, Chen, Chiao-Chi, Hsu, Yi-Hua, Chen, Hui-Mei, Chiu, Feng-Lan, Kuo, Hung-Chih, Chang, Chen, Chern, Yijuang

Journal:

Annals of Neurology

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

40

Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor

Wang, Shyi-Chyi, Lai, Hsing-Lin, Chiu, Yi-Ting, Ou, Ren, Huang, Chuen-Lin, Chern, Yijuang

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 740 KB

english, 2007

41

Erythropoietin Receptors Induced by Dimethyl Sulfoxide Exhibit Positive Cooperativity Associated with an Amplified Biologic Response

Shuji Yonekura, Yijuang Chern, Kelly A. Donahue, Laurie Feldman, Gary J. Vanasse and Arthur J. Sytkowski

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 885 KB

english, 1991

42

Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect

Sun, Chia-Sui, Lee, Chi-Chang, Li, Yi-Ni, Yao-Chen Yang, Sunny, Lin, Chih-Hsiang, Chang, Yi-Che, Liu, Po-Fan, He, Ruei-Yu, Wang, Chih-Hsien, Chen, Wenlung, Chern, Yijuang, Jen-Tse Huang, Joseph

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

43

Targeting ENT1 and adenosine tone for the treatment of Huntington’s disease

Kao, Yu-Han, Lin, Meng-Syuan, Chen, Chiung-Mei, Wu, Yih-Ru, Chen, Hui-Mei, Lai, Hsing-Lin, Chern, Yijuang, Lin, Chun-Jung

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 688 KB

english, 2017

44

Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning

Chang, Ching-Pang, Lee, Cheng-Ta, Hou, Wen-Hsien, Lin, Meng-Syuan, Lai, Hsing-Lin, Chien, Chen-Li, Chang, Chen, Cheng, Pei-Lin, Lien, Cheng-Chang, Chern, Yijuang

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.22 MB

english, 2016

45

Altered behavioral responses to gamma-aminobutyric acid pharmacological agents in a mouse model of Huntington's disease

Hsu, Yi-Ting, Chang, Ya-Gin, Chang, Ching-Pang, Siew, Jian-Jing, Chen, Hui-Mei, Tsai, Chon-Haw, Chern, Yijuang

Journal:

Movement Disorders

Year:

2017

Language:

english

File:

PDF, 782 KB

english, 2017

46

Advancing a high throughput glycotope-centric glycomics workflow based on nanoLC-MS 2 -product dependent-MS 3 analysis of permethylated glycans

Hsiao, Cheng-Te, Wang, Po-Wei, Chang, Hua-Chien, Chen, Yen-Ying, Wang, Shui-Hua, Chern, Yijuang, Khoo, Kay-Hooi

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 2.67 MB

english, 2017

47

GSK3β negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons

Chien, Ting, Weng, Yu-Ting, Chang, Shu-Yung, Lai, Hsing-Lin, Chiu, Feng-Lan, Kuo, Hung-Chih, Chuang, De-Maw, Chern, Yijuang

Journal:

Molecular Psychiatry

Year:

2018

Language:

english

File:

PDF, 5.57 MB

english, 2018

48

Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease

Lee, Chia-Chia, Chang, Ching-Pang, Lin, Chun-Jung, Lai, Hsing-Lin, Kao, Yu-Han, Cheng, Sin-Jhong, Chen, Hui-Mei, Liao, Yu-Ping, Faivre, Emilie, Buée, Luc, Blum, David, Fang, Jim-Min, Chern, Yijuang

Journal:

Molecular Neurobiology

Year:

2018

Language:

english

File:

PDF, 5.00 MB

english, 2018

49

The type VI adenylyl cyclase protects cardiomyocytes from β-adrenergic stress by a PKA/STAT3-dependent pathway

Wu, Yu-Shuo, Chen, Chien-Chang, Chien, Chen-Li, Lai, Hsing-Lin, Jiang, Si-Tse, Chen, Yong-Cyuan, Lai, Lin-Ping, Hsiao, Wei-Fan, Chen, Wen-Pin, Chern, Yijuang

Journal:

Journal of Biomedical Science

Year:

2017

Language:

english

File:

PDF, 3.16 MB

english, 2017

50

The Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease

Blum, David, Chern, Yijuang, Domenici, Maria Rosaria, Buée, Luc, Lin, Chien-Yu, Rea, William, Ferré, Sergi, Popoli, Patrizia

Journal:

Journal of Caffeine and Adenosine Research

Year:

2018

Language:

english

File:

PDF, 342 KB

english, 2018

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